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The Cell Danger Response: Inflammation and the Healing Cycle

Inflammation is the body’s normal response to danger. The body’s inflammatory response is meant to be transient – when that response is ongoing, and especially when the inciting event (pathogens, toxic elements) persists, the normal tamping down of inflammation doesn’t occur. When inflammation persists and the Healing Cycle is not completed the clinical presentation is an outcome of their genetic tendencies.

Naviaux RK. Metabolic features of the cell danger response.

Other perpetuating factors of a persistent Cell Danger Response can include:

  • Concurrent infectious loads (fungi, parasites, viruses, dysbiosis, occult dental infections, PANS. Symptoms of some infections may be suppressed until other infections are treated.
  • Structural issues, lax ligaments, Ehlers Danlos Syndrome (EDS), Cranial-Cervical Instability, vagal nerve issues.
  • Increased intestinal permeability – food allergies, increased toxin load, translocation between vagus nerve at the gut up to the brain, decreased nutrient absorption, a stressed liver.
  • Hypercoagulability – excess soluble fibrin or elevated homocysteine.
  • Psychological defense strategies, PTSD, OCD, anxiety.
  • Early childhood adverse events (physical and/or psychological).
  • Don’t ignore the potential of chronic jaw infections from root canals and old wisdom teeth extraction sites to derail treatment.
  • Sinus colonization – It’s more than Marcons!

See more information about treatment of complex chronic illness at GMA.

Chronic Fatigue Syndrome, Complex Chronic Illness, Eric Gordon MD, Immune Issues, Lyme Disease + Coinfections, Mast Cell Activation Syndrome (MCAS), Mold + Mycotoxin Illness